Sachdev published the first negative study of Transcranial Magnetic Stimulation (TMS) for depression, the first TMS treatment study of Obsessive Compulsive Disorder ( OCD), and the first study that examined the effect of different frequencies of TMS on an animal model of depression. Other work has been in the areas of late-onset Schizophrenia and secondary schizophrenia (including head injuries and schizophrenia-like psychosis). In particular, akathisia and its subtypes were characterised, including the development of a rating scale and research diagnostic criteria.
The major contribution of the NPI to psychiatric research has been in the field of Movement disorders, such as drug-induced Akathisia, tardive dystonia, Neuroleptic malignant syndrome, Tourette Syndrome, golfer's cramp and Psychomotor retardation in Melancholia. He has played a leading role in the development of higher training in Neuropsychiatry through his leadership of the International Neuropsychiatric Association (INA), and the Neuropsychiatry Section of the RANZCP.
Sachdev is the Clinical Director of the NPI at the Prince of Wales Hospital. He became a Fellow of the Royal Australian & New Zealand College of Psychiatrists (FRANZCP) in 1985. He received his MBBS from the All-India Institute of Medical Sciences (AIIMS) in 1978, his MD in psychiatry from AIIMS in 1981, and his PhD in psychiatry from UNSW in 1991. Sachdev was born in Ludhiana, India and went to school in Solan, in the foothills of the Himalayas.
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